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TargetCarbonic anhydrase 7
LigandBDBM50408534
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1739478 (CHEMBL4155228)
Ki 1.8±n/a nM
Citation Angeli, Adi Cesare Mannelli, LLucarini, EPeat, TSGhelardini, CSupuran, CT Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects. Eur J Med Chem154:210-219 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase 7
Synonyms:CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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  Blast E-value cutoff:
BDBM50408534
n/a
NameBDBM50408534
Synonyms:CHEMBL4162595
TypeSmall organic molecule
Emp. Form.C13H13NO2SSe
Mol. Mass.326.27
SMILES[#7]S(=O)(=O)c1ccc([Se;v2][#6]-c2ccccc2)cc1
Structure
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