| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50408526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1739478 (CHEMBL4155228) |
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| Ki | 0.930000±n/a nM |
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| Citation |  Angeli, A; di Cesare Mannelli, L; Lucarini, E; Peat, TS; Ghelardini, C; Supuran, CT Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects. Eur J Med Chem154:210-219 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50408526 |
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| n/a |
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| Name | BDBM50408526 |
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| Synonyms: | CHEMBL4163381 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N2O5SSe |
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| Mol. Mass. | 503.43 |
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| SMILES | [#6]-[#6](=O)-[#8]-c1ccccc1-[#6](=O)-[#7]-c1ccc([Se;v2][#6]-c2ccc(cc2)S([#7])(=O)=O)cc1 |
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| Structure | 
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