| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50018637 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_148992 |
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| Ki | 9.6±n/a nM |
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| Citation |  Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Structure-activity relationships of cyclic opioid peptide analogues containing a phenylalanine residue in the 3-position. J Med Chem30:2094-9 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44503.11 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
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| Residue: | 398 |
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| Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50018637 |
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| n/a |
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| Name | BDBM50018637 |
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| Synonyms: | 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,10,13-trioxo-1,4,9triaza-cyclotridecane-5-carboxylic acid amide | CHEMBL68177 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34N6O6 |
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| Mol. Mass. | 538.5955 |
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| SMILES | N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC(=O)NCCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O |
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| Structure | 
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