| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50065646 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1743306 (CHEMBL4177816) |
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| IC50 | 0.214000±n/a nM |
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| Citation |  Tuo, W; Leleu-Chavain, N; Spencer, J; Sansook, S; Millet, R; Chavatte, P Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. J Med Chem60:4-46 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL) |
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| Type: | Enzyme |
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| Mol. Mass.: | 33505.38 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q8R431 |
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| Residue: | 303 |
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| Sequence: | MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLG
HSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRID
SSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGAR
CLP
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| BDBM50065646 |
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| n/a |
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| Name | BDBM50065646 |
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| Synonyms: | CHEMBL3087181 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N4O5 |
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| Mol. Mass. | 434.4446 |
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| SMILES | O=C(N1CCC(CC1)C(c1ccc2OCOc2c1)c1ccc2OCOc2c1)n1cncn1 |
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| Structure | 
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