| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Steroid hormone receptor ERR2 |
|---|
| Ligand | BDBM50455428 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1754410 (CHEMBL4189170) |
|---|
| EC50 | 630±n/a nM |
|---|
| Citation |  Lin, H; Doebelin, C; Patouret, R; Garcia-Ordonez, RD; Chang, MR; Dharmarajan, V; Bayona, CR; Cameron, MD; Griffin, PR; Kamenecka, TM Design, synthesis, and evaluation of simple phenol amides as ERR? agonists. Bioorg Med Chem Lett28:1313-1319 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Steroid hormone receptor ERR2 |
|---|
| Name: | Steroid hormone receptor ERR2 |
|---|
| Synonyms: | ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 48061.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_11254 |
|---|
| Residue: | 433 |
|---|
| Sequence: | MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP
MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC
EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG
GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL
TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV
YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
MHKLFLEMLEAKV
|
|
|
|---|
| BDBM50455428 |
|---|
| n/a |
|---|
| Name | BDBM50455428 |
|---|
| Synonyms: | CHEMBL4205664 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N2O2 |
|---|
| Mol. Mass. | 312.4061 |
|---|
| SMILES | CCN(CC)c1ccc(CCNC(=O)c2ccc(O)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
