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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Stromelysin-1 | ||
| Ligand | BDBM50457775 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1760638 (CHEMBL4195646) | ||
| IC50 | 37280±n/a nM | ||
| Citation |  Wang, CG; Yao, WN; Zhang, B; Hua, J; Liang, D; Wang, HS Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migration. Bioorg Med Chem Lett28:2413-2417 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Stromelysin-1 | |||
| Name: | Stromelysin-1 | ||
| Synonyms: | MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 53973.13 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08254 | ||
| Residue: | 477 | ||
| Sequence: |
| ||
| BDBM50457775 | |||
| n/a | |||
| Name | BDBM50457775 | ||
| Synonyms: | CHEMBL451902 | Robustaflavone-4''-Methyl Ether | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H20O10 | ||
| Mol. Mass. | 552.4845 | ||
| SMILES | COc1ccc(cc1-c1c(O)cc2oc(cc(=O)c2c1O)-c1ccc(O)cc1)-c1cc(=O)c2c(O)cc(O)cc2o1 |(4.11,6.46,;4.1,4.92,;2.77,4.15,;1.43,4.92,;.1,4.16,;.1,2.62,;1.43,1.85,;2.77,2.61,;4.09,1.84,;4.09,.3,;2.75,-.46,;5.42,-.47,;6.75,.29,;8.08,-.49,;9.43,.28,;9.44,1.83,;8.09,2.62,;8.1,4.16,;6.75,1.84,;5.42,2.61,;5.44,4.15,;10.76,-.5,;10.74,-2.04,;12.07,-2.81,;13.41,-2.05,;14.74,-2.83,;13.41,-.5,;12.09,.26,;-1.23,1.86,;-1.23,.31,;-2.58,-.46,;-2.59,-2,;-3.92,.31,;-5.25,-.46,;-5.25,-2,;-6.58,.31,;-6.58,1.86,;-7.91,2.63,;-5.25,2.63,;-3.92,1.86,;-2.58,2.64,)| | ||
| Structure | 
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