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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Stromelysin-1 | ||
| Ligand | BDBM50457776 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1760638 (CHEMBL4195646) | ||
| IC50 | 74340±n/a nM | ||
| Citation |  Wang, CG; Yao, WN; Zhang, B; Hua, J; Liang, D; Wang, HS Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migration. Bioorg Med Chem Lett28:2413-2417 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Stromelysin-1 | |||
| Name: | Stromelysin-1 | ||
| Synonyms: | MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 53973.13 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08254 | ||
| Residue: | 477 | ||
| Sequence: |
| ||
| BDBM50457776 | |||
| n/a | |||
| Name | BDBM50457776 | ||
| Synonyms: | CHEMBL4208646 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H22O10 | ||
| Mol. Mass. | 554.5004 | ||
| SMILES | COc1ccc(cc1-c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1)C1CC(=O)c2c(O)cc(O)cc2O1 |(41.47,-11.31,;40.14,-12.08,;38.8,-11.32,;38.8,-9.76,;37.46,-9,;36.13,-9.77,;36.13,-11.32,;37.46,-12.09,;37.46,-13.63,;36.14,-14.41,;34.8,-13.65,;36.15,-15.94,;37.48,-16.71,;37.49,-18.25,;38.81,-15.94,;38.81,-14.39,;40.14,-13.62,;41.48,-14.39,;41.48,-15.94,;40.14,-16.7,;40.14,-18.24,;42.81,-13.62,;44.14,-14.39,;45.48,-13.63,;45.48,-12.08,;46.81,-11.31,;44.13,-11.31,;42.8,-12.09,;34.8,-9,;34.8,-7.46,;33.47,-6.69,;33.47,-5.15,;32.14,-7.46,;30.81,-6.68,;30.82,-5.14,;29.48,-7.44,;29.47,-8.99,;28.14,-9.76,;30.8,-9.76,;32.13,-8.99,;33.46,-9.77,)| | ||
| Structure | 
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