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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Matrix metalloproteinase-9 | ||
| Ligand | BDBM50129952 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1760639 (CHEMBL4195647) | ||
| IC50 | 2580±n/a nM | ||
| Citation |  Wang, CG; Yao, WN; Zhang, B; Hua, J; Liang, D; Wang, HS Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migration. Bioorg Med Chem Lett28:2413-2417 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Matrix metalloproteinase-9 | |||
| Name: | Matrix metalloproteinase-9 | ||
| Synonyms: | 67 kDa matrix metalloproteinase-9 | 82 kDa matrix metalloproteinase-9 | 92 kDa gelatinase | 92 kDa type IV collagenase | CLG4B | GELB | Gelatinase B | MMP-9 | MMP9 | MMP9_HUMAN | Matrix metalloproteinase 9 (MMP-9) | Matrix metalloproteinase-9 (MMP-9) | Matrix metalloproteinase-9 (MMP9) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 78452.28 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14780 | ||
| Residue: | 707 | ||
| Sequence: |
| ||
| BDBM50129952 | |||
| n/a | |||
| Name | BDBM50129952 | ||
| Synonyms: | 2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one | 8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one | Amentoflavone | CHEMBL63354 | cid_5281600 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H18O10 | ||
| Mol. Mass. | 538.4579 | ||
| SMILES | Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)| | ||
| Structure | 
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