| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM50022530 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196420 |
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| IC50 | >100000±n/a nM |
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| Citation |  Iizuka, K; Kamijo, T; Kubota, T; Akahane, K; Umeyama, H; Kiso, Y New human renin inhibitors containing an unnatural amino acid, norstatine. J Med Chem31:701-4 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | RENI_RAT | Ren | Ren1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44272.67 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_222765 |
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| Residue: | 402 |
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| Sequence: | MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGE
FIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYT
ACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG
GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSL
QLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL
ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
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| BDBM50022530 |
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| n/a |
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| Name | BDBM50022530 |
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| Synonyms: | 3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-propionylamino)-3-(1H-imidazol-4-yl)-propionylamino]-2-hydroxy-5-methyl-hexanoic acid methyl ester | CHEMBL350425 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H41N5O6 |
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| Mol. Mass. | 579.6871 |
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| SMILES | COC(=O)C(O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(CC(=O)N(C)C)Cc1cccc2ccccc12 |
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| Structure | 
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