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TargetCyclin-C
LigandBDBM50248631
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1768107 (CHEMBL4220219)
IC50 5.0±n/a nM
Citation Philip, SKumarasiri, MTeo, TYu, MWang, S Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy? J Med Chem61:5073-5092 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cyclin-C
Name:Cyclin-C
Synonyms:CCNC | CCNC_HUMAN | Cyclin C | SRB11 homolog | hSRB11
Type:PROTEIN
Mol. Mass.:33244.88
Organism:Homo sapiens (Human)
Description:ChEMBL_107900
Residue:283
Sequence:
MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ
VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRF
SYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV
NDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQ
WKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
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  Blast E-value cutoff:
BDBM50248631
n/a
NameBDBM50248631
Synonyms:CHEMBL4080906
TypeSmall organic molecule
Emp. Form.C30H36N2O3
Mol. Mass.472.6184
SMILES[H][C@@]12CC[C@H](c3ccc4ccncc4c3)[C@@]1(C)CC=C1C=C3[C@@H](O)[C@H](O)[C@H](C[C@]33CC[C@]21O3)N(C)C |r,t:21,23|
Structure
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