| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-C |
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| Ligand | BDBM50459995 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1768104 (CHEMBL4220216) |
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| IC50 | 4.0±n/a nM |
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| Citation |  Philip, S; Kumarasiri, M; Teo, T; Yu, M; Wang, S Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy? J Med Chem61:5073-5092 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-C |
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| Name: | Cyclin-C |
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| Synonyms: | CCNC | CCNC_HUMAN | Cyclin C | SRB11 homolog | hSRB11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33244.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107900 |
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| Residue: | 283 |
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| Sequence: | MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ
VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRF
SYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV
NDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQ
WKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
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| BDBM50459995 |
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| n/a |
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| Name | BDBM50459995 |
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| Synonyms: | CHEMBL4225966 | US11471446, Compound DBA-10 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18Br2N4 |
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| Mol. Mass. | 414.138 |
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| SMILES | Cc1c(Br)c(Br)c2CCCn3c(nc1c23)N1CCNCC1 |
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| Structure | 
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