| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM50460493 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1769583 |
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| Ki | 5000±n/a nM |
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| Citation |  Sosi?, I; Mitrovi?, A; ?uri?, H; Knez, D; Brodnik ?ugelj, H; ?tefane, B; Kos, J; Gobec, S Cathepsin B inhibitors: Further exploration of the nitroxoline core. Bioorg Med Chem Lett28:1239-1247 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM50460493 |
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| n/a |
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| Name | BDBM50460493 |
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| Synonyms: | CHEMBL4228921 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21N5O5 |
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| Mol. Mass. | 447.4433 |
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| SMILES | Oc1c(cc([N+]([O-])=O)c2cccnc12)C(=O)NCC1CCN(CC1)c1nc2ccccc2o1 |
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| Structure | 
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