| Reaction Details |
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 | Report a problem with these data |
| Target | Chitinase B |
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| Ligand | BDBM50462584 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1775690 (CHEMBL4232682) |
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| IC50 | 22±n/a nM |
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| Citation |  Unver, MY; Gierse, RM; Ritchie, H; Hirsch, AKH Druggability Assessment of Targets Used in Kinetic Target-Guided Synthesis. J Med Chem61:9395-9409 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chitinase B |
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| Name: | Chitinase B |
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| Synonyms: | CHIB_SERMA | chiB |
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| Type: | Enzyme |
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| Mol. Mass.: | 55462.70 |
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| Organism: | Serratia marcescens |
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| Description: | P11797 |
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| Residue: | 499 |
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| Sequence: | MSTRKAVIGYYFIPTNQINNYTETDTSVVPFPVSNITPAKAKQLTHINFSFLDINSNLEC
AWDPATNDAKARDVVNRLTALKAHNPSLRIMFSIGGWYYSNDLGVSHANYVNAVKTPAAR
TKFAQSCVRIMKDYGFDGVDIDWEYPQAAEVDGFIAALQEIRTLLNQQTIADGRQALPYQ
LTIAGAGGAFFLSRYYSKLAQIVAPLDYINLMTYDLAGPWEKITNHQAALFGDAAGPTFY
NALREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMMEGVPSAKIVMGVPFYGRAFKGVS
GGNGGQYSSHSTPGEDPYPNADYWLVGCDECVRDKDPRIASYRQLEQMLQGNYGYQRLWN
DKTKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQQLGGVMFWHLGQDNRNGDLLAALDR
YFNAADYDDSQLDMGTGLRYTGVGPGNLPIMTAPAYVPGTTYAQGALVSYQGYVWQTKWG
YITSAPGSDSAWLKVGRLA
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| BDBM50462584 |
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| n/a |
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| Name | BDBM50462584 |
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| Synonyms: | CHEMBL4245260 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H41N11O4 |
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| Mol. Mass. | 703.7927 |
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| SMILES | CNC(=O)NC(=N)NCCC[C@H](NC(=O)Cn1nncc1CO\N=C\c1ccnc2ccccc12)C(=O)N(Cc1ccccc1)Cc1ccccc1 |r| |
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| Structure | 
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