| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
|---|
| Ligand | BDBM50463170 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1777818 (CHEMBL4234810) |
|---|
| IC50 | 9800±n/a nM |
|---|
| Citation |  Nigam, R; Babu, KR; Ghosh, T; Kumari, B; Akula, D; Rath, SN; Das, P; Anindya, R; Khan, FA Indenone derivatives as inhibitor of human DNA dealkylation repair enzyme AlkBH3. Bioorg Med Chem26:4100-4112 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
|---|
| Name: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
|---|
| Synonyms: | ABH3 | ALKB3_HUMAN | ALKBH3 | Alkylated DNA repair protein alkB homolog 3 | DEPC-1 | DEPC1 | Prostate cancer antigen 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33382.86 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_108024 |
|---|
| Residue: | 286 |
|---|
| Sequence: | MEEKRRRARVQGAWAAPVKSQAIAQPATTAKSHLHQKPGQTWKNKEHHLSDREFVFKEPQ
QVVRRAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDVKEADWILEQLCQDVPWKQRTG
IREDITYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLRTLKNRIEENTGHTFNSLLCNL
YRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGDYTYVERVKIPLD
HGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYPDPRGAPW
|
|
|
|---|
| BDBM50463170 |
|---|
| n/a |
|---|
| Name | BDBM50463170 |
|---|
| Synonyms: | CHEMBL4239759 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H17ClO2 |
|---|
| Mol. Mass. | 360.833 |
|---|
| SMILES | COc1ccc(cc1)C1=C(Cl)C(=O)c2ccc(cc12)-c1ccc(C)cc1 |c:9| |
|---|
| Structure | 
|
|---|
Search and Browse
