| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-(Acyl-carrier-protein) reductase II |
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| Ligand | BDBM50464588 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1781839 (CHEMBL4253356) |
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| IC50 | 1750±n/a nM |
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| Citation |  Hu, Y; Shen, Y; Wu, X; Tu, X; Wang, GX Synthesis and biological evaluation of coumarin derivatives containing imidazole skeleton as potential antibacterial agents. Eur J Med Chem143:958-969 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-(Acyl-carrier-protein) reductase II |
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| Name: | Enoyl-(Acyl-carrier-protein) reductase II |
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| Synonyms: | Enoyl-(Acyl-carrier-protein) reductase II | fabK |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33389.23 |
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| Organism: | Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) |
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| Description: | ChEMBL_117863 |
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| Residue: | 319 |
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| Sequence: | MKTRITELLNIKYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGGNAPKEVVKANIDKIKS
MTDKPFGVNIMLLSPFVDDIVDLVIEEGVKVVTTGAGNPGKYMERFHEAGITVIPVVPSV
ALAKRMEKLGADAIITEGMEAGGHIGKLTTMTLVRQVVDAVTIPVIAAGGIADGRGAAAG
FMLGADAVQVGTRFVVAKESNAHPNYKAKILKAKDIDTAVSAQVVGHPVRALKNKLVTTY
SQAEKDYLAGRISINEIEELGAGALRNAVVDGDVINGSVMAGQIAGLIKSEETCQEILED
IYSGARQVILSEASRWSDL
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| BDBM50464588 |
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| n/a |
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| Name | BDBM50464588 |
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| Synonyms: | CHEMBL4283591 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N2O3 |
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| Mol. Mass. | 354.4427 |
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| SMILES | Cc1cn(CCCCCCCCOc2ccc3ccc(=O)oc3c2)cn1 |
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| Structure | 
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