Reaction Details | |||
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Target | Tyrosine-protein kinase Mer | ||
Ligand | BDBM50469349 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1804040 (CHEMBL4276332) | ||
IC50 | 3.1±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein kinase Mer | |||
Name: | Tyrosine-protein kinase Mer | ||
Synonyms: | MER | MER intracellular domain/EGFR extracellular domain chimera | MERTK | MERTK_HUMAN | Proto-oncogene c-Mer | Proto-oncogene tyrosine-protein kinase MER | Receptor tyrosine kinase MerTK | Tyrosine-protein kinase Mer | ||
Type: | PROTEIN | ||
Mol. Mass.: | 110234.77 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_1498723 | ||
Residue: | 999 | ||
Sequence: |
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BDBM50469349 | |||
n/a | |||
Name | BDBM50469349 | ||
Synonyms: | CHEMBL4281432 | ||
Type | Small organic molecule | ||
Emp. Form. | C28H40N6O | ||
Mol. Mass. | 476.6568 | ||
SMILES | CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1cccc(c1)N1CCN(C)CC1 |r,wU:13.12,wD:16.16,3.3,(4.25,-14.92,;5.58,-14.15,;6.91,-14.93,;8.25,-14.16,;8.25,-12.62,;9.58,-14.93,;10.91,-14.16,;10.92,-12.61,;12.24,-11.84,;13.58,-12.61,;15.06,-12.13,;15.97,-13.38,;15.06,-14.64,;15.8,-15.98,;17.34,-16,;18.08,-17.36,;17.28,-18.68,;18.03,-20.03,;15.74,-18.64,;15,-17.3,;13.58,-14.16,;12.25,-14.93,;15.77,-10.76,;14.94,-9.47,;15.65,-8.11,;17.2,-8.04,;18.02,-9.34,;17.31,-10.7,;19.56,-9.28,;20.38,-10.58,;21.91,-10.52,;22.63,-9.16,;24.17,-9.1,;21.81,-7.86,;20.27,-7.91,)| | ||
Structure | ![]() |