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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Vasopressin V1a receptor | ||
| Ligand | BDBM50469545 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1804356 (CHEMBL4276648) | ||
| Ki | 2949±n/a nM | ||
| Citation |  Cheignon, C; Cordeau, E; Prache, N; Cantel, S; Martinez, J; Subra, G; Arnaudguilhem, C; Bouyssiere, B; Enjalbal, C Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling. J Med Chem61:10173-10184 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Vasopressin V1a receptor | |||
| Name: | Vasopressin V1a receptor | ||
| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor | ||
| Type: | Receptor | ||
| Mol. Mass.: | 46820.18 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P37288 | ||
| Residue: | 418 | ||
| Sequence: |
| ||
| BDBM50469545 | |||
| n/a | |||
| Name | BDBM50469545 | ||
| Synonyms: | CHEMBL4283439 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C33H45N3O8S | ||
| Mol. Mass. | 643.791 | ||
| SMILES | CCOc1ccc2N(C(=O)[C@@]3(CC[C@@H](CC3)OCCN3CCOCC3)c2c1)S(=O)(=O)c1ccc(cc1OC)C(=O)NC(C)(C)C |r,wU:10.9,13.16,(37.72,-41.64,;39.05,-40.87,;40.39,-41.64,;41.72,-40.87,;41.72,-39.32,;43.05,-38.56,;44.38,-39.32,;45.84,-38.84,;46.75,-40.1,;48.29,-40.1,;45.84,-41.34,;44.75,-42.42,;45.15,-43.91,;46.64,-44.31,;47.73,-43.22,;47.33,-41.74,;47.04,-45.8,;48.52,-46.2,;49.61,-45.11,;51.09,-45.5,;52.18,-44.41,;53.67,-44.81,;54.07,-46.3,;52.98,-47.39,;51.49,-46.99,;44.38,-40.86,;43.06,-41.63,;46.24,-37.36,;45.84,-35.87,;44.75,-36.96,;47.73,-36.97,;48.82,-38.05,;50.3,-37.65,;50.7,-36.17,;49.61,-35.08,;48.13,-35.48,;47.04,-34.39,;45.55,-34.79,;52.18,-35.77,;52.58,-34.29,;53.27,-36.86,;54.76,-36.47,;55.85,-37.55,;55.16,-34.98,;56.24,-36.07,)| | ||
| Structure | 
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