| Reaction Details |
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 | Report a problem with these data |
| Target | Sporulation kinase A |
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| Ligand | BDBM50471729 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_37761 (CHEMBL650776) |
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| IC50 | >500000±n/a nM |
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| Citation |  Macielag, MJ; Demers, JP; Fraga-Spano, SA; Hlasta, DJ; Johnson, SG; Kanojia, RM; Russell, RK; Sui, Z; Weidner-Wells, MA; Werblood, H; Foleno, BD; Goldschmidt, RM; Loeloff, MJ; Webb, GC; Barrett, JF Substituted salicylanilides as inhibitors of two-component regulatory systems in bacteria. J Med Chem41:2939-45 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sporulation kinase A |
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| Name: | Sporulation kinase A |
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| Synonyms: | KINA_BACSU | Sporulation kinase A | Stage II sporulation protein F | Stage II sporulation protein J | gsiC | kinA | scoD | spoIIF | spoIIJ |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69161.05 |
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| Organism: | Bacillus subtilis (strain 168) |
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| Description: | ChEMBL_105028 |
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| Residue: | 606 |
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| Sequence: | MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGEMIGSFLKTFLHEEDQF
LVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAERTEREIILKMKVLEEETGH
QSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISVKGKIVYVNSAMLSMLGAKSK
DAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQTWKRLDGTPVHLEVKASPTVYK
NQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHNGKWVFMNESGISLFE
AATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQKTESEIVKQSWFTFQNRVIYTEMVCI
PTTFFGEAAVQVILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQL
MKPTMEGNEHYFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQ
ANLNGIFIRTSYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHV
TVKDEGEGIPEKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFK
ISFPKK
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| BDBM50471729 |
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| n/a |
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| Name | BDBM50471729 |
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| Synonyms: | CHEMBL419162 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25Cl2NO2 |
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| Mol. Mass. | 394.335 |
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| SMILES | CC(C)(C)c1cc(C(=O)Nc2ccc(Cl)c(Cl)c2)c(O)c(c1)C(C)(C)C |
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| Structure | 
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