| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase |
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| Ligand | BDBM50472269 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_80692 (CHEMBL690787) |
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| EC50 | >9750±n/a nM |
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| Citation |  Holý, A; Günter, J; Dvoráková, H; Masojídková, M; Andrei, G; Snoeck, R; Balzarini, J; De Clercq, E Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base. J Med Chem42:2064-86 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase |
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| Name: | Thymidine kinase |
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| Synonyms: | 2.7.1.21 | HHV3M2gp38 | HHV3_gp38 | HHV3gp38 | ORF36 | TK | Thymidine kinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37846.07 |
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| Organism: | Human herpesvirus 3 |
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| Description: | ChEMBL_14068 |
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| Residue: | 341 |
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| Sequence: | MSTDKTDVKMGVLRIYLDGAYGIGKTTAAEEFLHHFAITPNRILLIGEPLSYWRNLAGED
AICGIYGTQTRRLNGDVSPEDAQRLTAHFQSLFCSPHAIMHAKISALMDTSTSDLVQVNK
EPYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPAEPPGTNLVVCTVSLPSH
LSRVSKRARPGETVNLPFVMVLRNVYIMLINTIIFLKTNNWHAGWNTLSFCNDVFKQKLQ
KSECIKLREVPGIEDTLFAVLKLPELCGEFGNILPLWAWGMETLSNCLRSMSPFVLSLEQ
TPQHAAQELKTLLPQMTPANMSSGAWNILKELVNAVQDNTS
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| BDBM50472269 |
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| n/a |
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| Name | BDBM50472269 |
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| Synonyms: | CHEMBL293418 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H45N6O4P |
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| Mol. Mass. | 512.6257 |
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| SMILES | CC(C)CCCCCOP(=O)(COCCn1cnc2c(N)nc(N)nc12)OCCCCCC(C)C |
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| Structure | 
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