| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase |
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| Ligand | BDBM50472274 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_61076 (CHEMBL674916) |
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| EC50 | >30000±n/a nM |
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| Citation |  Holý, A; Günter, J; Dvoráková, H; Masojídková, M; Andrei, G; Snoeck, R; Balzarini, J; De Clercq, E Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base. J Med Chem42:2064-86 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase |
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| Name: | Thymidine kinase |
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| Synonyms: | KITH_HHV1S | TK | Thymidine kinase | UL23 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40883.42 |
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| Organism: | Human herpesvirus 1 (strain SC16) (HHV-1) (Human herpes simplex virus1) |
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| Description: | ChEMBL_213 |
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| Residue: | 376 |
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| Sequence: | MASYPGHQHASAFDQAARSRGHSNRRTALRPRRQQEATEVRPEQKMPTLLRVYIDGPHGM
GKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVV
MTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMG
SMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYG
LLANTVRYLQGGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAP
NGDLYNVFAWALDVLAKRLRPMHVFILDYDQSPAGCRDALLQLTSGMIQTHVTTPGSIPT
ICDLARTFAREMGEAN
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| BDBM50472274 |
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| n/a |
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| Name | BDBM50472274 |
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| Synonyms: | CHEMBL62595 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H43ClN5O4P |
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| Mol. Mass. | 532.056 |
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| SMILES | CC(C)CCCCCOP(=O)(COCCn1cnc2c(Cl)nc(N)nc12)OCCCCCC(C)C |
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| Structure | 
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