| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50481582 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_610130 (CHEMBL1074495) |
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| Ki | 0.310000±n/a nM |
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| Citation |  Ghosh, AK; Gemma, S; Simoni, E; Baldridge, A; Walters, DE; Ide, K; Tojo, Y; Koh, Y; Amano, M; Mitsuya, H Synthesis and biological evaluation of novel allophenylnorstatine-based HIV-1 protease inhibitors incorporating high affinity P2-ligands. Bioorg Med Chem Lett20:1241-6 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50481582 |
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| n/a |
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| Name | BDBM50481582 |
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| Synonyms: | CHEMBL601052 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H41N3O8S |
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| Mol. Mass. | 627.748 |
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| SMILES | [H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)C(=O)N1CSC(C)(C)[C@H]1C(=O)NCc1ccc(CO)cc1C |r| |
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| Structure | 
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