| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Ligand | BDBM50483195 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_690866 (CHEMBL1634228) |
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| IC50 | 10000±n/a nM |
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| Citation |  Nakayama, J; Uemura, Y; Nishiguchi, K; Yoshimura, N; Igarashi, Y; Sonomoto, K Ambuic acid inhibits the biosynthesis of cyclic peptide quormones in gram-positive bacteria. Antimicrob Agents Chemother53:580-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Name: | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Synonyms: | CP11A_RAT | Cyp11a | Cyp11a-1 | Cyp11a1 | Cytochrome P450 11A1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60603.33 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_50353 |
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| Residue: | 526 |
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| Sequence: | MLAKGLCLRSVLVKSCQPFLSPVWQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINL
YHFLRENGTHRIHYHHMQNFQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYL
VPPWVAYHQYYQRPIGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVL
HRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFH
TSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLY
SLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQA
QGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMG
RESSFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENF
RIEVQSIRDVGTKFNLILMPEKPIFFNFQPLKQDLGSTMPRKGDTV
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| BDBM50483195 |
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| n/a |
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| Name | BDBM50483195 |
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| Synonyms: | Ambuic Acid |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26O6 |
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| Mol. Mass. | 350.4061 |
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| SMILES | [H][C@]12O[C@@]1(C\C=C(/C)C(O)=O)C(=O)C(\C=C\CCCCC)=C(CO)[C@@H]2O |r,t:21| |
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| Structure | 
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