| Reaction Details |
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 | Report a problem with these data |
| Target | Bifunctional protein GlmU |
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| Ligand | BDBM50483325 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_708879 (CHEMBL1664948) |
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| Ki | 23±n/a nM |
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| Citation |  Pereira, MP; Blanchard, JE; Murphy, C; Roderick, SL; Brown, ED High-throughput screening identifies novel inhibitors of the acetyltransferase activity of Escherichia coli GlmU. Antimicrob Agents Chemother53:2306-11 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bifunctional protein GlmU |
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| Name: | Bifunctional protein GlmU |
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| Synonyms: | Bifunctional protein (GlmU) | GLMU_ECOLI | Glucosamine-1-phosphate N-acetyltransferase | UDP-N-acetylglucosamine pyrophosphorylase | glmU | yieA |
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| Type: | Enzyme |
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| Mol. Mass.: | 49189.50 |
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| Organism: | Escherichia coli |
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| Description: | P0ACC7 |
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| Residue: | 456 |
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| Sequence: | MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGD
LLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDA
KPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADM
KRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQ
SEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKN
SVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSK
AGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGAT
IAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
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| BDBM50483325 |
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| n/a |
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| Name | BDBM50483325 |
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| Synonyms: | CHEMBL1652297 | Mac0029665 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N4O4S5 |
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| Mol. Mass. | 544.754 |
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| SMILES | O=C(CSc1nnc(SCC(=O)NCCSCc2ccco2)s1)NCCSCc1ccco1 |
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| Structure | 
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