BindingDB PrimarySearch

Found 39 hits with Last Name = 'blanchard' and Initial = 'je'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bifunctional protein GlmU (Escherichia coli)	BDBM50294336 (5-amino-2-(4-aminophenylamino)benzenesulfonic acid...) Show SMILES Nc1ccc(Nc2ccc(N)cc2S(O)(=O)=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Competitive inhibition of Acetyltransferase activity of Escherichia coli BL21(DE3) GlmU in presence of AcCoA				Antimicrob Agents Chemother 53: 2306-11 (2009) Article DOI: 10.1128/AAC.01572-08 BindingDB Entry DOI: 10.7270/Q2VT1VXG
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Bifunctional protein GlmU (Escherichia coli)	BDBM50483325 (CHEMBL1652297 \| Mac0029665) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Competitive inhibition of Acetyltransferase activity of Escherichia coli BL21(DE3) GlmU in presence of AcCoA				Antimicrob Agents Chemother 53: 2306-11 (2009) Article DOI: 10.1128/AAC.01572-08 BindingDB Entry DOI: 10.7270/Q2VT1VXG
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Bifunctional protein GlmU (Escherichia coli)	BDBM50483326 (CHEMBL1652296 \| Mac0008028) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	404	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Competitive inhibition of Acetyltransferase activity of Escherichia coli BL21(DE3) GlmU in presence of AcCoA				Antimicrob Agents Chemother 53: 2306-11 (2009) Article DOI: 10.1128/AAC.01572-08 BindingDB Entry DOI: 10.7270/Q2VT1VXG
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370860 (CHEMBL219268) Show SMILES NNC(=O)CNC(=O)c1ccccc1C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370870 (CHEMBL218090) Show SMILES Cc1ccccc1NC(=O)C(C(F)(F)F)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370869 (CHEMBL220764) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68271 (M-31850) Show SMILES CCCNCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370861 (CHEMBL221848) Show SMILES COc1c(F)cc(C(=O)NCC(=O)NN)c(F)c1F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370865 (CHEMBL221706) Show SMILES NNS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370853 (CHEMBL221182) Show SMILES Cc1ccc(cc1)S(=O)(=O)NN Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370850 (CHEMBL373750) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370867 (CHEMBL221705) Show SMILES NNS(=O)(=O)c1ccc(s1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370855 (CHEMBL218737) Show SMILES NNC(=O)CNC(=O)c1ccccc1[N+]([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68272 (LU79953) Show SMILES CCCNCCCNCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM84610 (5-(3,5-dichlorophenoxy)-N-(4-pyrdinyl)-2- furamide...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	5.5	37
Research Institute, Hospital for Sick Children					Assay Description Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.				Chembiochem 9: 2650-62 (2008) Article DOI: 10.1002/cbic.200800304 BindingDB Entry DOI: 10.7270/Q2JQ0ZJK
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370857 (CHEMBL220531) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370854 (CHEMBL220494) Show SMILES NNS(=O)(=O)c1cccc2c(N)cccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370864 (CHEMBL451558) Show SMILES NNS(=O)(=O)c1ccc(Cl)s1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM18046 (5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...) Show SMILES Cc1ccc(Sc2cccc3nc(N)nc(N)c23)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	5.5	37
Research Institute, Hospital for Sick Children					Assay Description Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.				Chembiochem 9: 2650-62 (2008) Article DOI: 10.1002/cbic.200800304 BindingDB Entry DOI: 10.7270/Q2JQ0ZJK
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370856 (CHEMBL376005) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370866 (CHEMBL219582) Show SMILES NNC(=O)CNC(=O)c1ccc(cc1)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370848 (CHEMBL218058) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68270 (5141402) Show SMILES OCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM50106194 (1,3-dioxo-1H-benz[de]isoquinoline \| 1,8-Naphthalim...) Show SMILES O=C1NC(=O)c2cccc3cccc1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM84609 (7,8-diethoxy-quinazoline 2,4-diamine, 1b) Show SMILES CCOc1ccc2c(N)nc(N)nc2c1OCC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	5.5	37
Research Institute, Hospital for Sick Children					Assay Description Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.				Chembiochem 9: 2650-62 (2008) Article DOI: 10.1002/cbic.200800304 BindingDB Entry DOI: 10.7270/Q2JQ0ZJK
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370858 (CHEMBL220530) Show SMILES NNC(=O)CNC(=O)c1ccc(cc1)[N+]([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68269 (M-31867) Show SMILES CC(O)CCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370859 (CHEMBL383877) Show SMILES CC(=O)NCc1ccc(cc1)S(=O)(=O)NN Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370852 (CHEMBL219322) Show SMILES NNC(=O)CNC(=O)c1cccc(c1)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370851 (CHEMBL375564) Show SMILES COc1cccc(OC)c1C(=O)NCC(=O)NN Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM84608 (2,4-diamino-6-nitro-quinazoline, 1a) Show SMILES Nc1nc(N)c2cc(ccc2n1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	5.5	37
Research Institute, Hospital for Sick Children					Assay Description Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.				Chembiochem 9: 2650-62 (2008) Article DOI: 10.1002/cbic.200800304 BindingDB Entry DOI: 10.7270/Q2JQ0ZJK
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM84611 (2-methyl-N-pyridin-4-yl-benzamide, 2a) Show SMILES Cc1ccccc1C(=O)Nc1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	5.5	37
Research Institute, Hospital for Sick Children					Assay Description Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.				Chembiochem 9: 2650-62 (2008) Article DOI: 10.1002/cbic.200800304 BindingDB Entry DOI: 10.7270/Q2JQ0ZJK
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370863 (CHEMBL222116) Show SMILES NNC(=O)CNC(=O)c1cc(N)cc(N)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68268 (M-31862) Show SMILES O=C1N(CCCc2ccccn2)C(=O)c2cccc3cccc1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+5	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68267 (M-31860) Show SMILES O=C1N(CC2CCCO2)C(=O)c2cccc3cccc1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370868 (CHEMBL218485) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM84612 (2,2-dimethyl-N-(4-pyridinyl)propanamide, 2b) Show SMILES CC(C)(C)C(=O)Nc1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	5.5	37
Research Institute, Hospital for Sick Children					Assay Description Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.				Chembiochem 9: 2650-62 (2008) Article DOI: 10.1002/cbic.200800304 BindingDB Entry DOI: 10.7270/Q2JQ0ZJK
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370849 (CHEMBL385118) Show SMILES NNC(=O)CNC(=O)Cc1cccc2ccccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair
Cystathionine beta-lyase MetC (Escherichia coli K-12)	BDBM50370862 (CHEMBL221962) Show SMILES NNC(=O)CNC(=O)c1cc2ccccc2cc1N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CBL				J Med Chem 50: 755-64 (2007) Article DOI: 10.1021/jm061132r BindingDB Entry DOI: 10.7270/Q2KS6SCJ
McMaster University Curated by ChEMBL					More data for this Ligand-Target Pair