| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protease |
|---|
| Ligand | BDBM50483337 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_715372 (CHEMBL1664701) |
|---|
| Ki | 0.068000±n/a nM |
|---|
| Citation |  Ghosh, AK; Chapsal, BD; Baldridge, A; Steffey, MP; Walters, DE; Koh, Y; Amano, M; Mitsuya, H Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation. J Med Chem54:622-34 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protease |
|---|
| Name: | Protease |
|---|
| Synonyms: | n/a |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 10904.79 |
|---|
| Organism: | Human immunodeficiency virus 1 (HIV-1) |
|---|
| Description: | Q9YQ12 |
|---|
| Residue: | 99 |
|---|
| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
|---|
| BDBM50483337 |
|---|
| n/a |
|---|
| Name | BDBM50483337 |
|---|
| Synonyms: | CHEMBL1651154 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H40N2O8S |
|---|
| Mol. Mass. | 576.701 |
|---|
| SMILES | [H][C@]12CCO[C@@]1([H])OCC[C@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(OC)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
