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TargetRNA-directed RNA polymerase
LigandBDBM50537559
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1969960 (CHEMBL4602778)
IC50 3000±n/a nM
Citation Ganta, NMGedda, GRathnakar, BSatyanarayana, MYamajala, BAhsan, MJJadav, SSBalaraju, T A review on HCV inhibitors: Significance of non-structural polyproteins. Eur J Med Chem164:576-601 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
RNA-directed RNA polymerase
Name:RNA-directed RNA polymerase
Synonyms:Hepatitis C virus NS5B RNA-dependent RNA polymerase | NS5B protein
Type:Protein
Mol. Mass.:25173.95
Organism:Hepatitis C virus
Description:Q8JXU8
Residue:229
Sequence:
RTEEAIYQCCDLDPQARVAIRSLTERLYVGGPLTNSRGENCGYRRRASGVLTTSCGNTLT
CYIKAQAACRAAGRQDCTMLVCGDDLVVICESAGVQEDAASLRAFTEAMTRYSAPPGDPP
QPEYDLELITSCSSNVSVAHDGAGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIM
FAPTLWVRMIMLTHFFSVLIARDQLEQALDCEIYGACYSIEPLLPPIIQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50537559
n/a
NameBDBM50537559
Synonyms:CHEMBL4640738
TypeSmall organic molecule
Emp. Form.C18H24ClNO3
Mol. Mass.337.841
SMILESCCCC1(CC(O)=O)OCCC2C1Nc1c2c(CC)ccc1Cl
Structure
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