| Reaction Details |
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 | Report a problem with these data |
| Target | Nonstructural protein 5A |
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| Ligand | BDBM50160199 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1969964 (CHEMBL4602782) |
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| IC50 | 500±n/a nM |
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| Citation |  Ganta, NM; Gedda, G; Rathnakar, B; Satyanarayana, M; Yamajala, B; Ahsan, MJ; Jadav, SS; Balaraju, T A review on HCV inhibitors: Significance of non-structural polyproteins. Eur J Med Chem164:576-601 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nonstructural protein 5A |
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| Name: | Nonstructural protein 5A |
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| Synonyms: | NS5A | Nonstructural protein 5A |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48587.20 |
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| Organism: | Hepatitis C virus |
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| Description: | ChEMBL_108438 |
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| Residue: | 447 |
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| Sequence: | SGSWLRDVWDWICTVLTDFKTWLQSKLLPRIPGVPFLSCQRGYKGVWRGDGIMHTTCPCG
AQITGHVKNGSMRIVGPKTCSNTWHGTFPINTYTTGPCTPSPAPNYSRALWRVAAEEYVE
VTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREEVTFMVGLN
QYLVGSQLPCEPEPDVTVLTSMLTDPSHITAETAGRRLARGSPPSLASSSASQLSAPSLK
ATCTTRHDSPDADLIEANLLWRQEMGGNITRVESENKVVILDSFDPLQAEEDEREVSVPA
EILRKSRKFPRAMPIWARPDYNPPLLESWKDPDYVPPVVHGCPLPPAKAPPIPPPRRKRT
VVLTESTVSSALAELATKTFGSSGSSAVDSGTATAPPDQLPGDGDSGSDVESYSSMPPLE
GEPGDPDLSDGSWSTMSEEASEDVVCC
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| BDBM50160199 |
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| n/a |
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| Name | BDBM50160199 |
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| Synonyms: | 6,7-Bis-(4-fluoro-phenyl)-pteridin-4-ol | CHEMBL182020 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H10F2N4O |
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| Mol. Mass. | 336.295 |
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| SMILES | Fc1ccc(cc1)-c1nc2nc[nH]c(=O)c2nc1-c1ccc(F)cc1 |
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| Structure | 
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