| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nonstructural protein 5A |
|---|
| Ligand | BDBM50537588 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1969964 (CHEMBL4602782) |
|---|
| IC50 | 17±n/a nM |
|---|
| Citation |  Ganta, NM; Gedda, G; Rathnakar, B; Satyanarayana, M; Yamajala, B; Ahsan, MJ; Jadav, SS; Balaraju, T A review on HCV inhibitors: Significance of non-structural polyproteins. Eur J Med Chem164:576-601 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nonstructural protein 5A |
|---|
| Name: | Nonstructural protein 5A |
|---|
| Synonyms: | NS5A | Nonstructural protein 5A |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 48587.20 |
|---|
| Organism: | Hepatitis C virus |
|---|
| Description: | ChEMBL_108438 |
|---|
| Residue: | 447 |
|---|
| Sequence: | SGSWLRDVWDWICTVLTDFKTWLQSKLLPRIPGVPFLSCQRGYKGVWRGDGIMHTTCPCG
AQITGHVKNGSMRIVGPKTCSNTWHGTFPINTYTTGPCTPSPAPNYSRALWRVAAEEYVE
VTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREEVTFMVGLN
QYLVGSQLPCEPEPDVTVLTSMLTDPSHITAETAGRRLARGSPPSLASSSASQLSAPSLK
ATCTTRHDSPDADLIEANLLWRQEMGGNITRVESENKVVILDSFDPLQAEEDEREVSVPA
EILRKSRKFPRAMPIWARPDYNPPLLESWKDPDYVPPVVHGCPLPPAKAPPIPPPRRKRT
VVLTESTVSSALAELATKTFGSSGSSAVDSGTATAPPDQLPGDGDSGSDVESYSSMPPLE
GEPGDPDLSDGSWSTMSEEASEDVVCC
|
|
|
|---|
| BDBM50537588 |
|---|
| n/a |
|---|
| Name | BDBM50537588 |
|---|
| Synonyms: | CHEMBL4643189 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C37H33ClFN3O4 |
|---|
| Mol. Mass. | 638.127 |
|---|
| SMILES | OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2ccc(cc2-c2ccc(Cl)cc2)N2CCCC2=O)cc1F |
|---|
| Structure | 
|
|---|
Search and Browse
