| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sepiapterin reductase |
|---|
| Ligand | BDBM50537645 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1970294 (CHEMBL4603112) |
|---|
| IC50 | 970±n/a nM |
|---|
| Citation |  Gao, H; Schneider, S; Andrews, P; Wang, K; Huang, X; Sparling, BA Virtual screening to identify potent sepiapterin reductase inhibitors. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sepiapterin reductase |
|---|
| Name: | Sepiapterin reductase |
|---|
| Synonyms: | SPR | SPRE_HUMAN | Sepiapterin reductase (SPR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 28050.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35270 |
|---|
| Residue: | 261 |
|---|
| Sequence: | MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG
LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV
NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML
FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK
LLSLLEKDEFKSGAHVDFYDK
|
|
|
|---|
| BDBM50537645 |
|---|
| n/a |
|---|
| Name | BDBM50537645 |
|---|
| Synonyms: | CHEMBL467988 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H15N3O2 |
|---|
| Mol. Mass. | 281.3092 |
|---|
| SMILES | Cc1nn(C)c2ncc(cc12)C(=O)c1cc(C)ccc1O |
|---|
| Structure | 
|
|---|
Search and Browse
