| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50491090 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_956569 (CHEMBL2380019) |
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| Ki | 11±n/a nM |
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| Citation |  Shook, BC; Chakravarty, D; Barbay, JK; Wang, A; Leonard, K; Alford, V; Powell, MT; Rassnick, S; Scannevin, RH; Carroll, K; Wallace, N; Crooke, J; Ault, M; Lampron, L; Westover, L; Rhodes, K; Jackson, PF Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists. Bioorg Med Chem Lett23:2688-91 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50491090 |
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| n/a |
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| Name | BDBM50491090 |
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| Synonyms: | CHEMBL2377109 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N3O2S |
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| Mol. Mass. | 351.422 |
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| SMILES | COc1ccccc1Cc1cc2c(N)nc(nc2s1)-c1ccc(C)o1 |
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| Structure | 
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