| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50492333 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_969194 (CHEMBL2404614) |
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| IC50 | 30960±n/a nM |
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| Citation |  Yang, S; Pannecouque, C; Daelemans, D; Ma, XD; Liu, Y; Chen, FE; De Clercq, E Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors. Eur J Med Chem65:134-43 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50492333 |
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| n/a |
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| Name | BDBM50492333 |
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| Synonyms: | CHEMBL2402856 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H18N4O2 |
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| Mol. Mass. | 394.4253 |
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| SMILES | N#Cc1ccc(Nc2nccc(Oc3ccc(OCc4ccccc4)cc3)n2)cc1 |
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| Structure | 
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