Reaction Details |
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Target | 3',5'-cyclic-AMP phosphodiesterase |
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Ligand | BDBM50038978 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_155848 (CHEMBL766944) |
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IC50 | >100000±n/a nM |
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Citation | Takase, Y; Saeki, T; Watanabe, N; Adachi, H; Souda, S; Saito, I Cyclic GMP phosphodiesterase inhibitors. 2. Requirement of 6-substitution of quinazoline derivatives for potent and selective inhibitory activity. J Med Chem37:2106-11 (1994) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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3',5'-cyclic-AMP phosphodiesterase |
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Name: | 3',5'-cyclic-AMP phosphodiesterase |
Synonyms: | Phosphodiesterase 4A |
Type: | PROTEIN |
Mol. Mass.: | 13615.65 |
Organism: | Sus scrofa |
Description: | ChEMBL_155848 |
Residue: | 118 |
Sequence: | PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVDIPSPTMKDHEKQQ
APRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNEDSSIPRFGVKTDQEELLAQEL
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BDBM50038978 |
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n/a |
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Name | BDBM50038978 |
Synonyms: | Benzo[1,3]dioxol-5-ylmethyl-(6,7,8-trimethoxy-quinazolin-4-yl)-amine | CHEMBL302299 |
Type | Small organic molecule |
Emp. Form. | C19H19N3O5 |
Mol. Mass. | 369.3713 |
SMILES | COc1cc2c(NCc3ccc4OCOc4c3)ncnc2c(OC)c1OC |
Structure |
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