| Reaction Details |
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 | Report a problem with these data |
| Target | Pantothenate synthetase |
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| Ligand | BDBM50497766 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1452794 (CHEMBL3365136) |
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| IC50 | >25000±n/a nM |
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| Citation |  Samala, G; Nallangi, R; Devi, PB; Saxena, S; Yadav, R; Sridevi, JP; Yogeeswari, P; Sriram, D Identification and development of 2-methylimidazo[1,2-a]pyridine-3-carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors. Bioorg Med Chem22:4223-32 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pantothenate synthetase |
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| Name: | Pantothenate synthetase |
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| Synonyms: | Chain A, Crystal Structure Of A Pantothenate Synthetase, Apo Enzyme In C2 Space Group | PANC_MYCTU | Pantothenate synthetase | panC |
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| Type: | n/a |
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| Mol. Mass.: | 32675.10 |
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| Organism: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
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| Description: | ChEMBL_102878 |
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| Residue: | 309 |
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| Sequence: | MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGS
VVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQP
GPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVA
VVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLD
AAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYR
AILESHWRN
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| BDBM50497766 |
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| n/a |
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| Name | BDBM50497766 |
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| Synonyms: | CHEMBL3212161 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13N5O3 |
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| Mol. Mass. | 323.3061 |
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| SMILES | Cc1nc2ccccn2c1C(=O)N\N=C\c1ccc(cc1)[N+]([O-])=O |
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| Structure | 
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