| Reaction Details |
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 | Report a problem with these data |
| Target | Elastase |
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| Ligand | BDBM50498105 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1465577 (CHEMBL3404730) |
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| IC50 | 425000±n/a nM |
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| Citation |  Hansen, MR; Jakobsen, TH; Bang, CG; Cohrt, AE; Hansen, CL; Clausen, JW; Le Quement, ST; Tolker-Nielsen, T; Givskov, M; Nielsen, TE Triazole-containing N-acyl homoserine lactones targeting the quorum sensing system in Pseudomonas aeruginosa. Bioorg Med Chem23:1638-50 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Elastase |
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| Name: | Elastase |
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| Synonyms: | ELAS_PSEAE | Pseudolysin | lasB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53687.94 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_619859 |
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| Residue: | 498 |
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| Sequence: | MKKVSTLDLLFVAIMGVSPAAFAADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKA
IRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTT
AAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFV
IDAKTGEVLDQWEGLAHAEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMN
SSTDDSKTTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFKLYRDWFGTSPLTHKLYMK
VHYGRSVENAYWDGTAMLFGDGATMFYPLVSLDVAAHEVSHGFTEQNSGLIYRGQSGGMN
EAFSDMAGEAAEFYMRGKNDFLIGYDIKKGSGALRYMDQPSRDGRSIDNASQYYNGIDVH
HSSGVYNRAFYLLANSPGWDTRKAFEVFVDANRYYWTATSNYNSGACGVIRSAQNRNYSA
ADVTRAFSTVGVTCPSAL
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| BDBM50498105 |
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| n/a |
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| Name | BDBM50498105 |
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| Synonyms: | CHEMBL3403858 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22N4O3 |
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| Mol. Mass. | 294.3495 |
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| SMILES | CCCCCCc1cn(CC(=O)N[C@H]2CCOC2=O)nn1 |r| |
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| Structure | 
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