| Reaction Details |
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 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 1 |
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| Ligand | BDBM50500139 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1546964 (CHEMBL3748067) |
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| IC50 | 7700±n/a nM |
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| Citation |  Röhrig, UF; Majjigapu, SR; Vogel, P; Zoete, V; Michielin, O Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J Med Chem58:9421-37 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Indoleamine 2,3-dioxygenase 1 |
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| Name: | Indoleamine 2,3-dioxygenase 1 |
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| Synonyms: | I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase |
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| Type: | Enzyme |
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| Mol. Mass.: | 45330.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14902 |
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| Residue: | 403 |
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| Sequence: | MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
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| BDBM50500139 |
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| n/a |
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| Name | BDBM50500139 |
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| Synonyms: | CHEMBL3745728 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H30O3 |
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| Mol. Mass. | 318.4504 |
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| SMILES | [H][C@@]12CC[C@@]3(C=O)C(O)CC(C=O)=CC[C@]3([H])[C@@]1(C)CCCC2(C)C |r,c:12| |
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| Structure | 
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