| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 1 |
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| Ligand | BDBM50034220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48875 (CHEMBL662131) |
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| IC50 | 25000±n/a nM |
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| Citation |  Koufaki, M; Polychroniou, V; Calogeropoulou, T; Tsotinis, A; Drees, M; Fiebig, HH; LeClerc, S; Hendriks, HR; Makriyannis, A Alkyl and alkoxyethyl antineoplastic phospholipids. J Med Chem39:2609-14 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 1 |
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| Name: | M-phase inducer phosphatase 1 |
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| Synonyms: | CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25 |
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| Type: | Protein |
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| Mol. Mass.: | 59090.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30304 |
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| Residue: | 524 |
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| Sequence: | MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP
ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
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| BDBM50034220 |
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| n/a |
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| Name | BDBM50034220 |
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| Synonyms: | 2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide | CHEMBL125 | MILTEFOSINE | [2-(Hexadecyloxy-hydroxy-phosphoryloxy)-ethyl]-trimethyl-ammonium | hexadecyl 2-(trimethyl-lambda~5~-azanyl)ethyl hydrogen phosphate | hexadecyl 2-(trimethylammonio)ethyl phosphate | hexadecyloxy-2-trimethylammonioethylphosphorate | hexadecylphosphocholine | hexadecylphosphocholine, miltefosine | n-hexadecylphosphocholine |
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| Type | Small organic molecule |
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| Emp. Form. | C21H46NO4P |
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| Mol. Mass. | 407.568 |
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| SMILES | CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C |
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| Structure | 
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