Reaction Details | |||
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Target | Integrin alpha-IIb/beta-3 | ||
Ligand | BDBM50062790 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_70180 (CHEMBL685829) | ||
IC50 | 20±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Integrin alpha-IIb/beta-3 | |||
Name: | Integrin alpha-IIb/beta-3 | ||
Synonyms: | Glycoprotein IIb/IIIa | ||
Type: | n/a | ||
Mol. Mass.: | n/a | ||
Description: | ASSAY_ID of EBI is 30109 | ||
Components: | This complex has 2 components. | ||
Component 1 | |||
Name: | Integrin beta-3 | ||
Synonyms: | CD_antigen=CD61 | GP3A | GPIIIa | ITB3_HUMAN | ITGB3 | Integrin alpha-V/beta-3/alpha-V/beta-5 | Platelet membrane glycoprotein IIIa | ||
Type: | Protein | ||
Mol. Mass.: | 87038.91 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P05106 | ||
Residue: | 788 | ||
Sequence: |
| ||
Component 2 | |||
Name: | Integrin alpha-IIb | ||
Synonyms: | CD_antigen=CD41 | GP2B | GPIIb | GPalpha IIb | Glycoprotein IIb | ITA2B_HUMAN | ITGA2B | ITGAB | Integrin alpha-IIb heavy chain | Integrin alpha-IIb light chain, form 1 | Integrin alpha-IIb light chain, form 2 | Integrin alpha-IIb/beta-3 | Integrin alpha-V/beta-3 and alpha-IIb/beta 3 | Platelet membrane glycoprotein IIb | ||
Type: | Protein | ||
Mol. Mass.: | 113354.85 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P08514 | ||
Residue: | 1039 | ||
Sequence: |
| ||
BDBM50062790 | |||
n/a | |||
Name | BDBM50062790 | ||
Synonyms: | ((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cyclohexanecarbonyl)-amino]-acetyl}-3-oxo-piperazin-2-yl)-acetic acid | CHEMBL358154 | ||
Type | Small organic molecule | ||
Emp. Form. | C19H30N6O7 | ||
Mol. Mass. | 454.4775 | ||
SMILES | NC(=N)NCC1CCC(CC1)C(=O)NCC(=O)N1CCN(CC(O)=O)C(=O)[C@@H]1CC(O)=O |wD:27.29,(-3.9,-10.25,;-2.57,-11.02,;-2.57,-12.56,;-1.23,-10.25,;.1,-11.02,;1.43,-10.25,;1.45,-8.71,;2.76,-7.94,;4.09,-8.73,;4.11,-10.27,;2.76,-11.04,;5.44,-7.94,;5.42,-6.42,;6.77,-8.73,;8.1,-7.94,;9.43,-8.73,;9.43,-10.27,;10.76,-7.94,;10.76,-6.42,;12.09,-5.63,;13.42,-6.42,;14.75,-5.65,;16.08,-6.42,;17.43,-5.65,;16.08,-7.96,;13.42,-7.94,;14.75,-8.73,;12.09,-8.71,;12.09,-10.25,;13.42,-11.02,;13.42,-12.56,;14.75,-10.25,)| | ||
Structure | ![]() |