| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM50066615 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_212379 (CHEMBL817625) |
|---|
| Ki | 29±n/a nM |
|---|
| Citation |  Shaw, KJ; Guilford, WJ; Dallas, JL; Koovakkaat, SK; McCarrick, MA; Liang, A; Light, DR; Morrissey, MM (Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa. J Med Chem41:3551-6 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 25790.52 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | P00760 |
|---|
| Residue: | 246 |
|---|
| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
|
|
|
|---|
| BDBM50066615 |
|---|
| n/a |
|---|
| Name | BDBM50066615 |
|---|
| Synonyms: | (E,Z)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-one | 2-[1-[4-amino(imino)methylphenyl]-(E)-methylidene]-7-[1-[4-amino(imino)methylphenyl]-(Z)-methylidene]-1-cycloheptanone | CHEMBL94336 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H24N4O |
|---|
| Mol. Mass. | 372.4629 |
|---|
| SMILES | NC(=N)c1ccc(\C=C2\CCCC\C(=C/c3ccc(cc3)C(N)=N)C2=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
