| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
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| Ligand | BDBM50513267 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1852733 (CHEMBL4353357) |
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| Ki | 30±n/a nM |
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| Citation |  Franchini, S; Sorbi, C; Linciano, P; Carnevale, G; Tait, A; Ronsisvalle, S; Buccioni, M; Del Bello, F; Cilia, A; Pirona, L; Denora, N; Iacobazzi, RM; Brasili, L 1,3-Dioxane as a scaffold for potent and selective 5-HT Eur J Med Chem176:310-325 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1D adrenergic receptor |
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| Name: | Alpha-1D adrenergic receptor |
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| Synonyms: | ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60485.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | adrenergic Alpha1D ADRA1D HUMAN::P25100 |
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| Residue: | 572 |
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| Sequence: | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
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| BDBM50513267 |
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| n/a |
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| Name | BDBM50513267 |
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| Synonyms: | CHEMBL4462768 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H29NO7 |
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| Mol. Mass. | 479.5217 |
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| SMILES | OC(=O)C(O)=O.C(COc1ccccc1)NC[C@@H]1CO[C@@H](O1)C(c1ccccc1)c1ccccc1 |r| |
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| Structure | 
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