Compile Data Set for Download or QSAR

Found 520 hits with Last Name = 'iacobazzi' and Initial = 'rm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.331	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540827 (CHEMBL4643239) Show SMILES OC(=O)C(O)=O.C(C1CSCS1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C16H23NS2.C2H2O4/c1-2-4-14(5-3-1)10-15-6-8-17(9-7-15)11-16-12-18-13-19-16;3-1(4)2(5)6/h1-5,15-16H,6-13H2;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513275 (CHEMBL4458714) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-24-14-8-9-15-25(24)29-19-18-27-17-16-23-20-30-26(31-23,21-10-4-2-5-11-21)22-12-6-3-7-13-22;3-1(4)2(5)6/h2-15,23,27H,16-20H2,1H3;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50540826 (CHEMBL4647871) Show SMILES OC(=O)C(O)=O.CC1(C)SCC(CN2CCC(Cc3ccccc3)CC2)S1 Show InChI InChI=1S/C18H27NS2.C2H2O4/c1-18(2)20-14-17(21-18)13-19-10-8-16(9-11-19)12-15-6-4-3-5-7-15;3-1(4)2(5)6/h3-7,16-17H,8-14H2,1-2H3;(H,3,4)(H,5,6)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540828 (CHEMBL4633444) Show SMILES OC(=O)C(O)=O.OC(=O)C(O)=O.CC1(C)SCC(CN2CCN(Cc3ccccc3)CC2)S1 Show InChI InChI=1S/C17H26N2S2.2C2H2O4/c1-17(2)20-14-16(21-17)13-19-10-8-18(9-11-19)12-15-6-4-3-5-7-15;2*3-1(4)2(5)6/h3-7,16H,8-14H2,1-2H3;2*(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540830 (CHEMBL4646948) Show SMILES OC(=O)C(O)=O.CC1(C)OCC(CN2CCC(Cc3ccccc3)CC2)O1 Show InChI InChI=1S/C18H27NO2.C2H2O4/c1-18(2)20-14-17(21-18)13-19-10-8-16(9-11-19)12-15-6-4-3-5-7-15;3-1(4)2(5)6/h3-7,16-17H,8-14H2,1-2H3;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50409811 (CHEMBL1082862 | CHEMBL286003) Show SMILES COc1ccccc1OCCNCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H27NO4/c1-27-23-14-8-9-15-24(23)28-17-16-26-18-22-19-29-25(30-22,20-10-4-2-5-11-20)21-12-6-3-7-13-21/h2-15,22,26H,16-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.603	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50151272 (CHEMBL3769930) Show SMILES C(C1COC2(CCCCC2)O1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H30N2O2/c1-3-7-18(8-4-1)15-21-11-13-22(14-12-21)16-19-17-23-20(24-19)9-5-2-6-10-20/h1,3-4,7-8,19H,2,5-6,9-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 150 mins by scintillation counting analysis				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513270 (CHEMBL4467585) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCC1CCOC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-24-14-8-9-15-25(24)29-19-17-27-20-23-16-18-30-26(31-23,21-10-4-2-5-11-21)22-12-6-3-7-13-22;3-1(4)2(5)6/h2-15,23,27H,16-20H2,1H3;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.776	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50419716 (CHEMBL1946777) Show SMILES COc1ccccc1N1CCN(CC2COC(O2)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H30N2O3/c1-30-26-15-9-8-14-25(26)29-18-16-28(17-19-29)20-24-21-31-27(32-24,22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-15,24H,16-21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.813	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50210789 (CHEMBL3938383) Show SMILES COc1ccccc1OCCNCC1CSC2(CCCCC2)S1 Show InChI InChI=1S/C18H27NO2S2/c1-20-16-7-3-4-8-17(16)21-12-11-19-13-15-14-22-18(23-15)9-5-2-6-10-18/h3-4,7-8,15,19H,2,5-6,9-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513270 (CHEMBL4467585) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCC1CCOC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-24-14-8-9-15-25(24)29-19-17-27-20-23-16-18-30-26(31-23,21-10-4-2-5-11-21)22-12-6-3-7-13-22;3-1(4)2(5)6/h2-15,23,27H,16-20H2,1H3;(H,3,4)(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513258 (CHEMBL4462600) Show SMILES OC(=O)C(O)=O.C(COC(c1ccccc1)c1ccccc1)NCCOc1ccccc1 Show InChI InChI=1S/C23H25NO2/c1-4-10-20(11-5-1)23(21-12-6-2-7-13-21)26-19-17-24-16-18-25-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50540832 (CHEMBL4633796) Show SMILES OC(=O)C(O)=O.C(C1CSC2(CCCCC2)O1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H30N2OS.C2H2O4/c1-3-7-18(8-4-1)15-21-11-13-22(14-12-21)16-19-17-24-20(23-19)9-5-2-6-10-20;3-1(4)2(5)6/h1,3-4,7-8,19H,2,5-6,9-17H2;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 150 mins by scintillation counting analysis				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513258 (CHEMBL4462600) Show SMILES OC(=O)C(O)=O.C(COC(c1ccccc1)c1ccccc1)NCCOc1ccccc1 Show InChI InChI=1S/C23H25NO2/c1-4-10-20(11-5-1)23(21-12-6-2-7-13-21)26-19-17-24-16-18-25-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50026917 (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50026917 (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50210792 (CHEMBL3917316) Show SMILES C(COc1ccccc1)NCC1CSC2(CCCCC2)S1 Show InChI InChI=1S/C17H25NOS2/c1-3-7-15(8-4-1)19-12-11-18-13-16-14-20-17(21-16)9-5-2-6-10-17/h1,3-4,7-8,16,18H,2,5-6,9-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513271 (CHEMBL4439658) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCC(CO)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29NO4.C2H2O4/c1-28-23-14-8-9-15-24(23)29-17-16-26-18-22(19-27)30-25(20-10-4-2-5-11-20)21-12-6-3-7-13-21;3-1(4)2(5)6/h2-15,22,25-27H,16-19H2,1H3;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513266 (CHEMBL4588223) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCC1COC(OC1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO4/c1-28-24-14-8-9-15-25(24)29-17-16-27-18-21-19-30-26(31-20-21,22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-15,21,27H,16-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540816 (CHEMBL4634957) Show SMILES OC(=O)C(O)=O.C(C1CSC2(CCCCCC2)S1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H33NS2.C2H2O4/c1-2-7-13-22(12-6-1)24-18-21(25-22)17-23-14-10-20(11-15-23)16-19-8-4-3-5-9-19;3-1(4)2(5)6/h3-5,8-9,20-21H,1-2,6-7,10-18H2;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513265 (CHEMBL4582160) Show SMILES OC(=O)C(O)=O.C(COc1ccccc1)NCC1CCOC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H27NO3.C2H2O4/c1-4-10-21(11-5-1)25(22-12-6-2-7-13-22)28-18-16-24(29-25)20-26-17-19-27-23-14-8-3-9-15-23;3-1(4)2(5)6/h1-15,24,26H,16-20H2;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540826 (CHEMBL4647871) Show SMILES OC(=O)C(O)=O.CC1(C)SCC(CN2CCC(Cc3ccccc3)CC2)S1 Show InChI InChI=1S/C18H27NS2.C2H2O4/c1-18(2)20-14-17(21-18)13-19-10-8-16(9-11-19)12-15-6-4-3-5-7-15;3-1(4)2(5)6/h3-7,16-17H,8-14H2,1-2H3;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513263 (CHEMBL4570387) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNC[C@H]1CO[C@@H](O1)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-23-14-8-9-15-24(23)29-17-16-27-18-22-19-30-26(31-22)25(20-10-4-2-5-11-20)21-12-6-3-7-13-21;3-1(4)2(5)6/h2-15,22,25-27H,16-19H2,1H3;(H,3,4)(H,5,6)/t22-,26-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540829 (CHEMBL4637859) Show SMILES OC(=O)C(O)=O.OC(=O)C(O)=O.C(C1CSCS1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C15H22N2S2.2C2H2O4/c1-2-4-14(5-3-1)10-16-6-8-17(9-7-16)11-15-12-18-13-19-15;2*3-1(4)2(5)6/h1-5,15H,6-13H2;2*(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50210791 (CHEMBL3901382) Show SMILES COc1ccccc1OCCNCC1CSC2(CCCCC2)O1 Show InChI InChI=1S/C18H27NO3S/c1-20-16-7-3-4-8-17(16)21-12-11-19-13-15-14-23-18(22-15)9-5-2-6-10-18/h3-4,7-8,15,19H,2,5-6,9-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50210795 (CHEMBL3929328) Show SMILES COc1ccccc1N1CCN(CC2CSC3(CCCCC3)S2)CC1 Show InChI InChI=1S/C20H30N2OS2/c1-23-19-8-4-3-7-18(19)22-13-11-21(12-14-22)15-17-16-24-20(25-17)9-5-2-6-10-20/h3-4,7-8,17H,2,5-6,9-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50540815 (CHEMBL4642427) Show SMILES OC(=O)C(O)=O.C(C1CSC2(CCCC2)S1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H29NS2.C2H2O4/c1-2-6-17(7-3-1)14-18-8-12-21(13-9-18)15-19-16-22-20(23-19)10-4-5-11-20;3-1(4)2(5)6/h1-3,6-7,18-19H,4-5,8-16H2;(H,3,4)(H,5,6)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50210790 (CHEMBL3981480) Show SMILES COc1ccccc1OCCNCC1COC2(CCCCC2)O1 Show InChI InChI=1S/C18H27NO4/c1-20-16-7-3-4-8-17(16)21-12-11-19-13-15-14-22-18(23-15)9-5-2-6-10-18/h3-4,7-8,15,19H,2,5-6,9-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513259 (CHEMBL4526865) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNC[C@@H]1CO[C@@H](O1)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-23-14-8-9-15-24(23)29-17-16-27-18-22-19-30-26(31-22)25(20-10-4-2-5-11-20)21-12-6-3-7-13-21;3-1(4)2(5)6/h2-15,22,25-27H,16-19H2,1H3;(H,3,4)(H,5,6)/t22-,26+;/m1./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50540828 (CHEMBL4633444) Show SMILES OC(=O)C(O)=O.OC(=O)C(O)=O.CC1(C)SCC(CN2CCN(Cc3ccccc3)CC2)S1 Show InChI InChI=1S/C17H26N2S2.2C2H2O4/c1-17(2)20-14-16(21-17)13-19-10-8-18(9-11-19)12-15-6-4-3-5-7-15;2*3-1(4)2(5)6/h3-7,16H,8-14H2,1-2H3;2*(H,3,4)(H,5,6)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50409813 (CHEMBL1083181 | CHEMBL37883) Show SMILES C(COc1ccccc1)NCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H25NO3/c1-4-10-20(11-5-1)24(21-12-6-2-7-13-21)27-19-23(28-24)18-25-16-17-26-22-14-8-3-9-15-22/h1-15,23,25H,16-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540815 (CHEMBL4642427) Show SMILES OC(=O)C(O)=O.C(C1CSC2(CCCC2)S1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H29NS2.C2H2O4/c1-2-6-17(7-3-1)14-18-8-12-21(13-9-18)15-19-16-22-20(23-19)10-4-5-11-20;3-1(4)2(5)6/h1-3,6-7,18-19H,4-5,8-16H2;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513259 (CHEMBL4526865) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNC[C@@H]1CO[C@@H](O1)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-23-14-8-9-15-24(23)29-17-16-27-18-22-19-30-26(31-22)25(20-10-4-2-5-11-20)21-12-6-3-7-13-21;3-1(4)2(5)6/h2-15,22,25-27H,16-19H2,1H3;(H,3,4)(H,5,6)/t22-,26+;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513274 (CHEMBL4558985) Show SMILES OC(=O)C(O)=O.OCC(CNCCOc1ccccc1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27NO3.C2H2O4/c26-19-23(18-25-16-17-27-22-14-8-3-9-15-22)28-24(20-10-4-1-5-11-20)21-12-6-2-7-13-21;3-1(4)2(5)6/h1-15,23-26H,16-19H2;(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513265 (CHEMBL4582160) Show SMILES OC(=O)C(O)=O.C(COc1ccccc1)NCC1CCOC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H27NO3.C2H2O4/c1-4-10-21(11-5-1)25(22-12-6-2-7-13-22)28-18-16-24(29-25)20-26-17-19-27-23-14-8-3-9-15-23;3-1(4)2(5)6/h1-15,24,26H,16-20H2;(H,3,4)(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50210794 (CHEMBL3892434) Show SMILES COc1ccccc1N1CCN(CC2CSC3(CCCCC3)O2)CC1 Show InChI InChI=1S/C20H30N2O2S/c1-23-19-8-4-3-7-18(19)22-13-11-21(12-14-22)15-17-16-25-20(24-17)9-5-2-6-10-20/h3-4,7-8,17H,2,5-6,9-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50099434 (CHEMBL2234448) Show SMILES COc1ccccc1N1CCN(CC2COC3(CCCCC3)O2)CC1 Show InChI InChI=1S/C20H30N2O3/c1-23-19-8-4-3-7-18(19)22-13-11-21(12-14-22)15-17-16-24-20(25-17)9-5-2-6-10-20/h3-4,7-8,17H,2,5-6,9-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...				Eur J Med Chem 125: 435-452 (2017) Article DOI: 10.1016/j.ejmech.2016.09.050 BindingDB Entry DOI: 10.7270/Q2BG2R46
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513260 (CHEMBL4457585) Show SMILES OC(=O)C(O)=O.C(COc1ccccc1)NC[C@H]1CO[C@@H](O1)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C25H27NO3.C2H2O4/c1-4-10-20(11-5-1)24(21-12-6-2-7-13-21)25-28-19-23(29-25)18-26-16-17-27-22-14-8-3-9-15-22;3-1(4)2(5)6/h1-15,23-26H,16-19H2;(H,3,4)(H,5,6)/t23-,25-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50540831 (CHEMBL4639948) Show SMILES OC(=O)C(O)=O.OC(=O)C(O)=O.CC1(C)OCC(CN2CCN(Cc3ccccc3)CC2)O1 Show InChI InChI=1S/C17H26N2O2.2C2H2O4/c1-17(2)20-14-16(21-17)13-19-10-8-18(9-11-19)12-15-6-4-3-5-7-15;2*3-1(4)2(5)6/h3-7,16H,8-14H2,1-2H3;2*(H,3,4)(H,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513275 (CHEMBL4458714) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-24-14-8-9-15-25(24)29-19-18-27-17-16-23-20-30-26(31-23,21-10-4-2-5-11-21)22-12-6-3-7-13-22;3-1(4)2(5)6/h2-15,23,27H,16-20H2,1H3;(H,3,4)(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513271 (CHEMBL4439658) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCC(CO)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29NO4.C2H2O4/c1-28-23-14-8-9-15-24(23)29-17-16-26-18-22(19-27)30-25(20-10-4-2-5-11-20)21-12-6-3-7-13-21;3-1(4)2(5)6/h2-15,22,25-27H,16-19H2,1H3;(H,3,4)(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50540830 (CHEMBL4646948) Show SMILES OC(=O)C(O)=O.CC1(C)OCC(CN2CCC(Cc3ccccc3)CC2)O1 Show InChI InChI=1S/C18H27NO2.C2H2O4/c1-18(2)20-14-17(21-18)13-19-10-8-16(9-11-19)12-15-6-4-3-5-7-15;3-1(4)2(5)6/h3-7,16-17H,8-14H2,1-2H3;(H,3,4)(H,5,6)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513263 (CHEMBL4570387) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNC[C@H]1CO[C@@H](O1)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-23-14-8-9-15-24(23)29-17-16-27-18-22-19-30-26(31-22)25(20-10-4-2-5-11-20)21-12-6-3-7-13-21;3-1(4)2(5)6/h2-15,22,25-27H,16-19H2,1H3;(H,3,4)(H,5,6)/t22-,26-;/m0./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50513273 (CHEMBL4468507) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCCOC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27NO3/c1-26-22-14-8-9-15-23(22)27-18-16-25-17-19-28-24(20-10-4-2-5-11-20)21-12-6-3-7-13-21/h2-15,24-25H,16-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counter				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50513275 (CHEMBL4458714) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29NO4.C2H2O4/c1-28-24-14-8-9-15-25(24)29-19-18-27-17-16-23-20-30-26(31-23,21-10-4-2-5-11-21)22-12-6-3-7-13-22;3-1(4)2(5)6/h2-15,23,27H,16-20H2,1H3;(H,3,4)(H,5,6)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1A expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50540816 (CHEMBL4634957) Show SMILES OC(=O)C(O)=O.C(C1CSC2(CCCCCC2)S1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H33NS2.C2H2O4/c1-2-7-13-22(12-6-1)24-18-21(25-22)17-23-14-10-20(11-15-23)16-19-8-4-3-5-9-19;3-1(4)2(5)6/h3-5,8-9,20-21H,1-2,6-7,10-18H2;(H,3,4)(H,5,6)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Modena and Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assay				ACS Med Chem Lett 11: 1028-1034 (2020) Article DOI: 10.1021/acsmedchemlett.0c00129 BindingDB Entry DOI: 10.7270/Q2833WKN
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50409811 (CHEMBL1082862 | CHEMBL286003) Show SMILES COc1ccccc1OCCNCC1COC(O1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H27NO4/c1-27-23-14-8-9-15-24(23)28-17-16-26-18-22-19-29-25(30-22,20-10-4-2-5-11-20)21-12-6-3-7-13-21/h2-15,22,26H,16-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50513273 (CHEMBL4468507) Show SMILES OC(=O)C(O)=O.COc1ccccc1OCCNCCOC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27NO3/c1-26-22-14-8-9-15-23(22)27-18-16-25-17-19-28-24(20-10-4-2-5-11-20)21-12-6-3-7-13-21/h2-15,24-25H,16-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL					Assay Description Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...				Eur J Med Chem 176: 310-325 (2019) Article DOI: 10.1016/j.ejmech.2019.05.024 BindingDB Entry DOI: 10.7270/Q26976XT
					More data for this Ligand-Target Pair

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