| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interstitial collagenase |
|---|
| Ligand | BDBM50069617 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_70456 |
|---|
| IC50 | 106±n/a nM |
|---|
| Citation |  Bailey, S; Bolognese, B; Buckle, DR; Faller, A; Jackson, S; Louis-Flamberg, P; McCord, M; Mayer, RJ; Marshall, LA; Smith, DG Selective inhibition of low affinity IgE receptor (CD23) processing. Bioorg Med Chem Lett8:29-34 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Interstitial collagenase |
|---|
| Name: | Interstitial collagenase |
|---|
| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54010.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P03956 |
|---|
| Residue: | 469 |
|---|
| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
|
|
|
|---|
| BDBM50069617 |
|---|
| n/a |
|---|
| Name | BDBM50069617 |
|---|
| Synonyms: | (2R,3S)-N*4*-((S)-1-Carbamoyl-2-phenyl-ethyl)-2-cyanomethylsulfanylmethyl-N*1*-hydroxy-3-isobutyl-succinamide | CHEMBL324295 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H28N4O4S |
|---|
| Mol. Mass. | 420.526 |
|---|
| SMILES | CC(C)C[C@H]([C@H](CSCC#N)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
