| Reaction Details |
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 | Report a problem with these data |
| Target | Lymphokine-activated killer T-cell-originated protein kinase |
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| Ligand | BDBM50515042 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1859796 (CHEMBL4360652) |
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| IC50 | 21±n/a nM |
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| Citation |  Yuan, T; Qi, B; Jiang, Z; Dong, W; Zhong, L; Bai, L; Tong, R; Yu, J; Shi, J Dual FLT3 inhibitors: Against the drug resistance of acute myeloid leukemia in recent decade. Eur J Med Chem178:468-483 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lymphokine-activated killer T-cell-originated protein kinase |
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| Name: | Lymphokine-activated killer T-cell-originated protein kinase |
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| Synonyms: | 2.7.12.2 | CT84 | Cancer/testis antigen 84 | MAPKK-like protein kinase | Nori-3 | PBK | PDZ-binding kinase | SPK | Spermatogenesis-related protein kinase | T-LAK cell-originated protein kinase | TOPK | TOPK_HUMAN |
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| Type: | n/a |
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| Mol. Mass.: | 36072.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 322 |
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| Sequence: | MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPRGLSHSP
WAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGE
KSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFE
TIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEM
MTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVC
TNEDPKDRPSAAHIVEALETDV
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| BDBM50515042 |
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| n/a |
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| Name | BDBM50515042 |
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| Synonyms: | CHEMBL4593398 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14F3N5 |
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| Mol. Mass. | 357.3325 |
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| SMILES | FC(F)(F)c1n[nH]cc1-c1nc2ccc3[nH]ncc3c2c2CCCCc12 |
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| Structure | 
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