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TargetBeta-2 adrenergic receptor
LigandBDBM50072385
Substrate/Competitorn/a
Meas. Tech.ChEBML_38310
IC50 2000±n/a nM
Citation Naylor, EMColandrea, VJCandelore, MRCascieri, MAColwell, LFDeng, LFeeney, WPForrest, MJHom, GJMacIntyre, DEStrader, CDTota, LWang, PRWyvratt, MJFisher, MHWeber, AE 3-Pyridylethanolamines: potent and selective human beta 3 adrenergic receptor agonists. Bioorg Med Chem Lett8:3087-92 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor
Name:Beta-2 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50072385
n/a
NameBDBM50072385
Synonyms:CHEMBL320138 | N-(4-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenylsulfamoyl}-phenyl)-4-phenyl-butyramide
TypeSmall organic molecule
Emp. Form.C31H34N4O4S
Mol. Mass.558.691
SMILESO[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(NC(=O)CCCc3ccccc3)cc2)cc1)c1cccnc1
Structure
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