| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM50072853 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48483 (CHEMBL662061) |
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| Ki | 1700±n/a nM |
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| Citation |  Renatus, M; Bode, W; Huber, R; Stürzebecher, J; Stubbs, MT Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. J Med Chem41:5445-56 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54498.45 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1364435 |
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| Residue: | 492 |
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| Sequence: | MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
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| BDBM50072853 |
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| n/a |
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| Name | BDBM50072853 |
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| Synonyms: | 4-[3-(3-Diaminomethyl-phenyl)-2-(2,4,6-triisopropyl-benzenesulfonylamino)-propionyl]-piperazine-1-carboxylic acid ethyl ester | CHEMBL356007 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H49N5O5S |
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| Mol. Mass. | 615.827 |
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| SMILES | CCOC(=O)N1CCN(CC1)C(=O)C(Cc1cccc(c1)C(N)N)NS(=O)(=O)c1c(cc(cc1C(C)C)C(C)C)C(C)C |
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| Structure | 
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