| Reaction Details |
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 | Report a problem with these data |
| Target | Growth hormone secretagogue receptor type 1 |
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| Ligand | BDBM50073040 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_173122 |
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| EC50 | 60±n/a nM |
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| Citation |  Yang, L; Morriello, G; Prendergast, K; Cheng, K; Jacks, T; Chan, WW; Schleim, KD; Smith, RG; Patchett, AA Potent 3-spiropiperidine growth hormone secretagogues. Bioorg Med Chem Lett8:107-12 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth hormone secretagogue receptor type 1 |
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| Name: | Growth hormone secretagogue receptor type 1 |
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| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | GHSR_RAT | Ghrelin receptor | Ghsr | Growth hormone secretagogue receptor type 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40970.19 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_11556 |
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| Residue: | 364 |
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| Sequence: | MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGN
LLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQF
VSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVL
VGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWR
RRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQ
YCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKS
SINT
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| BDBM50073040 |
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| n/a |
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| Name | BDBM50073040 |
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| Synonyms: | 1N-[1-(1H-3-indolylmethyl)-2-oxo-2-spiro[2,3-dihydro-1H-indene-2,3'-(hexahydropyridine)]-1-yl-(1R)-ethyl]-2-amino-2-methylpropanamide | CHEMBL427806 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H34N4O2 |
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| Mol. Mass. | 458.5952 |
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| SMILES | CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCCC2(Cc3ccccc3C2)C1 |
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| Structure | 
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