Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50073337 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_157537 (CHEMBL764922) |
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Ki | 2100±n/a nM |
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Citation | Baker, CT; Salituro, FG; Court, JJ; Deininger, DD; Kim, EE; Li, B; Novak, PM; Rao, BG; Pazhanisamy, S; Schairer, WC; Tung, RD Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors. Bioorg Med Chem Lett8:3631-6 (1999) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50073337 |
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n/a |
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Name | BDBM50073337 |
Synonyms: | CHEMBL122564 | N-[(S)-3-(3-tert-Butyl-1-phenethyl-ureido)-2-hydroxy-propyl]-N-cyclopentylmethyl-4-methoxy-benzenesulfonamide |
Type | Small organic molecule |
Emp. Form. | C29H43N3O5S |
Mol. Mass. | 545.734 |
SMILES | COc1ccc(cc1)S(=O)(=O)N(C[C@@H](O)CN(CCc1ccccc1)C(=O)NC(C)(C)C)CC1CCCC1 |
Structure |
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