| Reaction Details |
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 | Report a problem with these data |
| Target | Proto-oncogene tyrosine-protein kinase Src |
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| Ligand | BDBM50074703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_202793 (CHEMBL809573) |
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| IC50 | >100000±n/a nM |
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| Citation |  Ettmayer, P; France, D; Gounarides, J; Jarosinski, M; Martin, MS; Rondeau, JM; Sabio, M; Topiol, S; Weidmann, B; Zurini, M; Bair, KW Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1). J Med Chem42:971-80 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proto-oncogene tyrosine-protein kinase Src |
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| Name: | Proto-oncogene tyrosine-protein kinase Src |
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| Synonyms: | Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src |
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| Type: | Protein |
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| Mol. Mass.: | 59838.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P12931 |
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| Residue: | 536 |
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| Sequence: | MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
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| BDBM50074703 |
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| n/a |
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| Name | BDBM50074703 |
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| Synonyms: | CHEMBL172299 | Phosphoric acid mono-[4-((5R,8S,11R,14S,19aS)-8-carbamoylmethyl-5,11-diisopropyl-4,7,10,13,16,19-hexaoxo-octadecahydro-3a,6,9,12,15,18-hexaaza-cyclopentacyclooctadecen-14-ylmethyl)-phenyl] ester |
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| Type | Small organic molecule |
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| Emp. Form. | C30H44N7O11P |
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| Mol. Mass. | 709.6844 |
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| SMILES | CC(C)[C@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(C)C |
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| Structure | 
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