| Reaction Details |
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 | Report a problem with these data |
| Target | B2 bradykinin receptor |
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| Ligand | BDBM50075187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_40107 |
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| Ki | 9200.0±n/a nM |
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| Citation |  Dziadulewicz, EK; Brown, MC; Dunstan, AR; Lee, W; Said, NB; Garratt, PJ The design of non-peptide human bradykinin B2 receptor antagonists employing the benzodiazepine peptidomimetic scaffold. Bioorg Med Chem Lett9:463-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| B2 bradykinin receptor |
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| Name: | B2 bradykinin receptor |
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| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44467.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
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| Residue: | 391 |
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| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
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| BDBM50075187 |
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| n/a |
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| Name | BDBM50075187 |
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| Synonyms: | CHEMBL442294 | N-[4-(3-Benzyl-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)-phenyl]-guanidine |
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| Type | Small organic molecule |
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| Emp. Form. | C29H25N5O |
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| Mol. Mass. | 459.5417 |
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| SMILES | [#7]\[#6](-[#7])=[#7]/c1ccc(cc1)-[#7]-1-c2ccccc2-[#6](=[#7]-[#6](-[#6]-c2ccccc2)-[#6]-1=O)-c1ccccc1 |c:19| |
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| Structure | 
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