| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor X |
|---|
| Ligand | BDBM50526351 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1899849 (CHEMBL4401964) |
|---|
| IC50 | 960±n/a nM |
|---|
| Citation |  Wang, J; Wu, M; Gao, C; Fu, H Semisynthesis of epoxy-pimarane diterpenoids from kirenol and their FXa inhibition activities. Bioorg Med Chem27:1320-1326 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor X |
|---|
| Name: | Coagulation factor X |
|---|
| Synonyms: | Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | F10 | FA10_HUMAN | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54726.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 488 |
|---|
| Sequence: | MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
|
|
|
|---|
| BDBM50526351 |
|---|
| n/a |
|---|
| Name | BDBM50526351 |
|---|
| Synonyms: | CHEMBL4561623 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H32O3 |
|---|
| Mol. Mass. | 308.4556 |
|---|
| SMILES | [H][C@@]12CC[C@](C)(CO)C=C1CC[C@]1([H])[C@](C)(CO)C[C@@H](O)C[C@@]21C |r,c:8| |
|---|
| Structure | 
|
|---|
Search and Browse
