| Reaction Details |
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 | Report a problem with these data |
| Target | 85/88 kDa calcium-independent phospholipase A2 |
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| Ligand | BDBM50529953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1911002 (CHEMBL4413448) |
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| IC50 | 90±n/a nM |
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| Citation |  Mouchlis, VD; Armando, A; Dennis, EA Substrate-Specific Inhibition Constants for Phospholipase A J Med Chem62:1999-2007 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 85/88 kDa calcium-independent phospholipase A2 |
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| Name: | 85/88 kDa calcium-independent phospholipase A2 |
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| Synonyms: | Calcium-independent phospholipase A2 | PLA2G6 | PLPL9_HUMAN | PLPLA9 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 89913.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_156048 |
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| Residue: | 806 |
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| Sequence: | MQFFGRLVNTFSGVTNLFSNPFRVKEVAVADYTSSDRVREEGQLILFQNTPNRTWDCVLV
NPRNSQSGFRLFQLELEADALVNFHQYSSQLLPFYESSPQVLHTEVLQHLTDLIRNHPSW
SVAHLAVELGIRECFHHSRIISCANCAENEEGCTPLHLACRKGDGEILVELVQYCHTQMD
VTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLL
LCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMA
RMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSK
DNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLLRTVGAEYCFPPIHG
VPAEQGSAAPHHPFSLERAQPPPISLNNLELQDLMHISRARKPAFILGSMRDEKRTHDHL
LCLDGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGM
YFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVRKPKVMLTGTLSDRQPAELHLFR
NYDAPETVREPRFNQNVNLRPPAQPSDQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNP
TLDAMTEIHEYNQDLIRKGQANKVKKLSIVVSLGTGRSPQVPVTCVDVFRPSNPWELAKT
VFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGTDIMLDEVSDTVLVN
ALWETEVYIYEHREEFQKLIQLLLSP
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| BDBM50529953 |
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| n/a |
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| Name | BDBM50529953 |
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| Synonyms: | CHEMBL4438490 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H37F2N3O5S2 |
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| Mol. Mass. | 849.962 |
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| SMILES | Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3\SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 |r| |
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| Structure | 
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